Exercise Pill – Can It Help You Lose Weight Without Exercising

Exercise Pill - Can It Help You Lose Weight Without Exercising

The Exercise Pill. Researchers in America may have discovered a way to make a pill that could replace exercise and help people to lose weight without the need to break a sweat.

For anyone who has such a hectic lifestyle they are unable to find the time to exercise, a pill like that could seem like a godsend.

An exercise pill could be equally attractive to people who spend most of their day sitting behind a desk or the steering wheel of a truck or bus.

Then there are the people who are dangerously overweight but cannot exercise because they are too old or have heath problems that may make exercising dangerous. However, nice as it may sound, the exercise replacement pill may not be available anytime soon.

The only studies so far have been conducted on mice. There is no way of knowing if humans will respond in the same way, or what the side effects are likely to be.

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woman runningThe researchers at the Salk Institute for Biological Studies in La Jolla, California, wanted to find out what physical endurance meant on the molecular level, see if it was feasible to replace training with a drug and develop an exercise pill. Previous studies, involving a drug called GW501516, had already proved effective for improving stamina and encouraging the body to burn fat faster, so the researchers decided to further explore its potential.

Tests involving obese mice, running on treadmills showed the drug successfully increased endurance by 70 percent.

The researchers also discovered the drug altered the activity of nearly 1000 genes. The ones that are necessary for breaking down and burning fat became more active, but others, including some that convert sugar into energy, showed inhibited activity.

According to a report published in the May edition of Cell Metabolism, mice that were not given the drug were only capable of running for 160 minutes. The ones that received it managed to sustain the activity for 270 minutes and were more insulin responsive and resistant to weight gain.

exercise pillCloser inspection of the data revealed this was due to the fact that one of the genes altered by the drug stopped burning sugar as a primary source of energy and began burning fat instead.

Subsequent analysis of the mice’s muscle tissue revealed the ones that had been given the drug did not have additional mitochondria (energy provider). The researchers saw this as proof that the drug can provide the same benefits as exercise.

“It means you can improve endurance to the equivalent level as someone in training, without all of the physical effort,” first author Weiwei Fan said in a press release.

The researchers are now trying to find a pharmaceutical company with the resources necessary to develop clinical trials and test the drug on humans. If the tests are successful, and an exercise pill is created, it could be a useful ally in the war against obesity and may also have value as a treatment for type 2 diabetes.

However, some experts are worried the drug could be used for less reputable reasons. Ali Tavassoli, professor of chemical biology at Southampton University, said an exercise pill could potentially be abused by athletes and horse trainers.

Pharmacologist Louise MacKenzie (University of Hertfordshire) has also raised some concerns.

She has studied the drug in the past and says high doses can cause nasty side effects. “It goes from being remarkably healthy to being the complete opposite, there’s no in-between,” MacKenzie said but admitted it was a good starting point for scientists looking for better ways to help people to improve their health. “I can definitely see a future where the problems are solved,” she said. “You just need to have enough clever scientists working on them.”

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Saxenda Injection For Weight Loss – Containing Liraglutide

Saxenda injectionSaxenda is an injectable weight loss treatment created and distributed by Novo Nordisk. The Therapeutic Goods Administration (TGA) has sanctioned its use for treating obesity and it’s been available via private doctor’s prescription since December 2015.

The daily Saxenda injections ease the weight loss process by suppressing the appetite. This allows people to reduce
their calorie intake without being plagued by hunger pangs. However, as with other TGA approved prescription weight loss medications, Saxenda has to be used with diet and exercise. This helps ensure the body experiences a calorie shortage that is sufficient to necessitate the burning of fat calories.

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What Is In The Formula

The active ingredient is a drug called Liraglutide. It was originally developed as a treatment to help manage diabetes, but when diabetics using the drug began losing weight it was also made available as a weight loss aid. The dose used for weigh loss purposes is higher than that needed for diabetes.

Weight Loss injectionLiraglutide appears to mimic the effects of the GLP-1 hormone created in the intestines. This hormone increases insulin secretion and sensitivity. It also slows acid secretion and gastric emptying.

The knock-on effect of this is the brain receives a message that misleads it into believing the stomach is full. The results of three early studies suggest people using the drug in conjunction with a low calorie meal plan and increased levels of physical activity may lose 2.5 times as much weight.

How to Use – comes in a pre-filled injector pen. Only one injection is required per day and it is important it goes into the skin tissue, avoiding the veins and muscles. The recommended injection areas are the upper arm, waist and thigh. New users will require coaching in the correct way to administer the drug, and the dosage is gradually increased over a 5-week period.

  • Week 1:6mg
  • Week 2: 2mg
  • Week 3:8mg
  • Week 4: 4mg
  • Week 5 onwards: 3mg

Saxenda Customer Comments

Some average customer comments read:

“The actual injection is not so bad. Just a little prick. But my skin gets very itchy afterwards. It’s not nice at all, but usually wears off after an hour or two. I’ve been using this stuff for around 5 weeks now and the total weight loss so far is 28lbs.” 

“The injections are a pain and the headaches and dizziness are even worse, but I’m dropping about 4lbs a week so I suppose it may be worthwhile in the end.”

“I’ve been using Saxenda for 6 weeks and it has helped me to lose 18 pounds. That doesn’t seem a lot to me. Especially for such an expensive drug. I also find it an unpleasant product to use. I need to lose weight, but don’t want to be a pincushion to do it. I’m going to try something else instead.” 

“My appetite is no longer a problem and I’m finally starting to lose weight, but the injections make me feel very sick and dizzy so I may have to stop.”

Side Effects Of Saxenda

Saxenda’s prescription-only status is not without good reason. The drug can aggravate certain medical conditions and is known to interact badly with some medications. Information provided on the manufacturer’s website also points out use of product entails a possible risk of thyroid tumours. However, this warning is based on the way some rodents reacted to the drug. It may not have this effect on humans.

Some of the common side effects related to Saxenda usage include nausea, vomiting, and changes to bowel movement. More serious side effects include extreme fatigue, shortness of breath, difficulty concentrating, and racing heart beat. Any Saxenda user who experiences serious negative reactions is advised to stop using the drug at once and seek medical advice.

Pricing and Availability

Saxenda is not subsidised by the Pharmaceutical Benefits Scheme (PBS), so it has to be purchased by private prescription at a cost of around $400 per month.

Although the price is daunting, most dieters will not need to concern themselves because they will be unable to get hold of a prescription. Australian law only permits doctors to prescribe the drug to people who have a BMI of 30 or higher. People who have a BMI of 27 to 29 may also be eligible for a prescription if they also suffer from at least one weight-related health problem, such as high cholesterol or type 2 diabetes.

Saxenda weight loss injection

Final Verdict

The TGA obviously has faith in the hunger suppressing abilities of Saxenda. If they didn’t it would not have been approved as a prescription only weight loss medication. Many dieters may not relish the idea of sticking a needle in their flesh every day though.

Even more will not have a BMI that is high enough to make them eligible for a prescription, and those who do obtain one are looking at a hefty monthly expense for the duration of the treatment. The side effects the drug presents are also an issue.

Saxenda may be good for weight loss, but some supplements are better and can offer pain-free weight loss without side effects for a fraction of the price.

Click here for a list of recommended weight loss products

Best Diet Pills For 2017 In Australia

Best Diet Pills for 2017

Setting about writing a list of the best diet pills for 2017 is not something we take lightly. When people visit this site looking for a safe and effective way to lose weight we want to give them the best advice available. Many diet diet pills are not what they seem. A lot of them do not work and those that do sometimes contain illegal drugs that are not declared, or have other ingredients that may make people ill.

In a world where obesity levels are rising this is a big problem. There’s a demand for diet pills that work, but the supply is limited. So limited, in fact, we are only confident enough to add three to our list, but we truly believe they are the best of the best and all of them have accrued such a wealth of positive feedback from customers we know we are not alone in our belief.

None of the products that made our list of best diet pills for 2017 are made in Australia, but they are all easy weight loss supplements to buy online and, in the case of PhenQ, there are no additional charges for shipping.

PhenQ

Buy PhenQ in AustraliaYou never heard the name PhenQ up until a couple of years ago, then suddenly everywhere you looked online people were talking about it. The manufacturers were so confident about its abilities they were offering a 60-day money back guarantee and it had this great new ingredient in it, called a-Lacys Reset, that can help you to lose weight fast. Nobody else seemed to be guaranteeing their diet pills for that long when PhenQ was launched, in 2015. That’s no longer the case but, to the best of our knowledge, PhenQ is still the only diet pill that contains a-Lacys Reset. These days PhenQ has even more going for it because over 190,000 people say it helped them to lose weight. It’s one of the most respected diet pills on the market.

Some diet pills are designed to help people to lose weight by working on their appetites and helping reduce the desire for food. Others speed up the metabolism to make calories burn away faster. Many boost energy levels or block fat, and a few work on the mood to make sure dieting doesn’t become depressing. A number of diet pills offer a combination of these benefits, but PhenQ does the lot.

Click Here to Learn More About PhenQ

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Phentaslim

Phentaslim reviewsPhentaslim is no newcomer to the market. People have been talking about this diet pill for a long time. They have a lot to say about it and all of it is good. It’s marketed as a “Maximum Strength Fat Burner” and, these days, it comes with a 60-day guarantee. The manufacturer obviously chose the name “Phentaslim” because it sounds like “Phentermine” and this is one of the many names used for the prescription only appetite suppressant Duromine. There’s a big demand for Duromine and a lot of people who can’t get it on prescription search online. Many of them will likely discover Phentaslim and, although it packs a similar punch, it does not cause side effects. Duromine does, so Phentaslim is the better option and a lot of people who use it believe it’s more powerful as well.

The fact that so many people write reviews saying Phentaslim is better than Duromine is not that surprising. The prescription weight loss drug has proven abilities, but it’s primarily an appetite suppressant. People who use it will find it easier to eat less food and this can cause the body to start burning its fat to get more energy. Phentaslim does this as well, but it also boosts the metabolism. This causes the body to burn the calories it does receive a lot faster than normal. Phentaslim also beats Duromine in a few other ways. It boosts energy levels, improves concentration, and delivers ingredients that cause the fat burning process to become more efficient.

Read More Reasons Why Phentaslim is a Good Alternative to Duromine

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Phen375

Phen375 ReviewLike the other other top diet pills for 2017, Phen375 is one of the most respected diet pills in Australia. The average weight loss with Phen375 appears to be 1.3 – 2.2kg (3 – 5lbs) a week, but a lot of customers who leave reviews brag they have lost much more. This diet pill has helped a lot of people to put their bad eating habits behind them and start living a healthier life; and we’ve read a number of reviews written by people who say Phen375 helped them to lose over 45kg (100lbs). Despite the product’s ongoing success, the marketing claims made for it are not overly brash or over the top. The manufacturer simply tells it like it is by stating the pills reduce food cravings, burn fat, and help you to lose weight.

Like Phentaslim, Phen375 is a very popular alternative to Duromine, that has no side effects to sully its reputation. Nobody who is trying to lose weight wants to feel unwell while they are slimming down, so this is important. In many ways Phen375 has more in common with Phentaslim than it does with Duromine because it boosts the metabolism and improves the body’s natural fat burning abilities. It suppresses the appetite as well, of course, so in that way it is not unlike Duromine. Apart from that, the only similarity is the “Phen” in the name.

Read Our Phen375 Review