Mysimba prescription-only anti-obesity medication

MySimba AustraliaMysimba is a prescription-only anti-obesity medication developed in the USA by Orexigen. The company was founded in 2002 and their only other product is called Contrave. However, Contrave and Mysimba are identical.

Both products contain the same two drugs, but the combination is distributed in the USA under the Contrave brand name and Orexigen has chosen to market the product as Mysimba in Europe and the UK.

Mysimba and Contrave contain Naltrexone and Bupropion. The latter is an antidepressant that can also help smokers become ex-smokers by helping to suppress the urge for nicotine. Naltrexone is an anti-addiction medication, but both posses limited appetite suppressing abilities which appear to be slightly enhanced when they are combined.

Which weight loss products are most effective – see results

How Mysimba Works

ContraveThe combined abilities of the two drugs provided by the Mysimba diet pill affects the way the brain and central nervous system regulates energy expenditure (calorie usage), the appetite and food cravings.

Orexigen state their research shows the combination of Bupropion and Naltrexone helps people to lose weight because Bupropion boosts dopamine levels in the brain. Some diet supplements are designed to provide hunger suppression in a similar manner because dopamine levels are known to effect the appetite.

However, Bupropion only works in this way for a limited amount of time and the appetite suppressing effect diminishes with use. Orexigen have conducted trials that suggest Naltrexone can help Bupropion to keep on working for longer and has the added benefit of making sweet food less enticing.

Mysimba Ingredient Profile

Each Mysimba diet pill contains:

  • Bupropion (78mg)
  • Naltrexone (90mg)

Usage Guidelines –  intended to be used alongside a calorie-restricted diet. Regular exercise is also recommended.

The pills have to be taken with water and should be swallowed whole. Chewing the pills or allowing them to dissolve in the mouth increases the likelihood of side effects. The dosage is increased on a weekly basis until the maximum dose of four pills per day is reached.

  • First week: One pill each morning
  • Second week: One pill in the morning and one pill in the evening
  • Third week: Two pills in the morning and one pill in the evening
  • Fourth week: Two pills in the morning and two more in the evening

Mysimba Scientific Trials

A number of studies have been conducted and, in one clinical trial, 50.8% of Mysimba showed a 5% bodyweight reduction at Week 16. This is interesting, but many over-the-counter supplements can do a lot more, so we are not particularly impressed by this result.

Mysimba close up

Important Usage Considerations and Potential Side Effects

The combination of Naltrexone and Bupropion incorporated in Mysimba diet pills is not suitable for women who are pregnant or nursing a child. It can also interact with some medications and may aggravate certain medical conditions.

Potential side effects include:

  • Anxiety
  • Difficulty sleeping
  • Headaches
  • Feelings of restlessness
  • Impaired concentration
  • Heart palpitations
  • Hot flushes
  • Dizziness
  • Nausea
  • Constipation
  • Muscular aches and pains

Some Mysimba users may experience side effects of a more dangerous nature, including liver damage and suicidal tendencies. When Mysimba was first sanctioned for use in Europe, health watchdogs were appalled and stated the low level of benefits provide, coupled with the relatively high risk of side effects, make use of the medication”too risky for only modest weight loss“.

What Past Users Are Saying About Mysimba

“I’m taking four pills per day, eating right, and getting plenty of exercise. I’ve been averaging a weight loss of around 3 pounds a week, but the pills make me feel quite sick and I’ve been getting a lot of headaches, so I’m not sure if I want to go on taking them.”

“I lost 13lbs in the first month with this medication. Apart from being a little constipated at times the side effects have not been too bad.”

“This stuff made me feel very sick and dizzy. I gave up using it after a week because I couldn’t stand it no more.”

“I used the pills for 3 weeks and lost 7lbs. It was nice to see a little progress, but I felt so unwell (headaches) it wasn’t worth the trade off.”

How Mysimba Compares to Other Options

Mysimba is obviously capable of helping people to lose weight, but the amount of weight loss reported suggests the medication is not as powerful as some dietary supplements. Side effects also appear to be a big problem for a lot of users.

Most other prescription-only weight loss medications, including Phentermine and Orlistat, are known to cause side effects as well, and the amount of weight loss they provide can be quite modest, so Mysimba is probably no better or worse than the other offerings doctors are allowed to prescribe.

However, good diet pills, like PhenQ and Capsiplex, can provide dieters with better results and do not offer the same range of side effects. Bearing in mind the fact that these products also come with a money back guarantee, they are easily the more sensible option.

Which diet pills are most effective – see results

Metermine Phentermine – Uses, Side Effects and Stockists

Metermine AustraliaMetermine is a brand of Phentermine manufactured by iNova Pharmaceuticals. Many people need to lose weight, and Metermine is respected for its ability to help people get slimmer, so it is a much sought after drug.

Unfortunately, it also presents health risks, so doctors are only permitted to prescribe it to people who are clinically obese.

Some people who want to lose weight find the restrictions hard to take and decide to search out an overseas supplier who will allow them to buy the drug online. This is not good thinking. Safer, more effective options are available.

Read our Review and Discover Why PhenQ is Better Than Metermine

How Does Metermine Work

Duromine 30mg AustraliaMetermine is an appetite suppressing drug that makes it easier for most people to be satisfied with less food, it works in a similar way to Duromine

The food we eat provides the body with the nutrients and calories that are necessary to maintain life.

Calories are needed for energy and the body is burning them 24-hours a day. Even the act of blinking the eyes requires two calories per blink. The problem is many people eat more calories per day than their body needs.

The extra calories are stored as fat and the body weight increases. Most people who are overweight understand why they have started tipping the scales in such an unfavourable manner, but resisting hunger urges is very difficult. Especially for anyone who has become used to overeating on a daily basis.

When it’s used alongside healthy eating habits and regular exercise, the appetite suppressing effects of Metermine can help ensure the body becomes so short of calories it has to start burning the calories stored in its fat.

Key Ingredients & Blend Potential

Each capsule contains Phentermine as an ion exchange resin complex.

Phentermine assists weight loss by causing the brain to stimulate the adrenal glands into releasing the neurotransmitters (norepinephrine, serotonin and dopamine) that are normally emitted during times of danger or exhilaration. This generally provides fast appetite suppression, but the level of hunger reduction experienced can vary from one person to the next.

How to Use – has to be used in conjunction with diet and exercise. Only one capsule is needed per day and should be taken with breakfast.

The capsule may contain 15mg, 30mg, or 40mg of Phentermine. The doctor prescribing the medication will decide which strength option is best for each patient’s individual needs.

The maximum treatment period is three months, but the doctor may decide to stop the treatment sooner if use of the medication does not appear to be helping patients to lose weight, if the side effects become too bad, or if the weight drops below the BMI threshold required for a Metermine prescription.

Metermine User Comments

A few average customer comments read:

“This medication is wonderful for controlling your eating. It’helped me to lose 38. pounds, but my doctor stopped the prescription when my BMI got down to 30. Now I’m going to have to look for something else because I’m still too fat.” 

“I started taking Metermine 4 days ago. It’s taken away my hunger cravings, but my skin feels very itchy most of the day and I’ve been having dizzy spells. I’m going to persist with it for another week and see if the side effects stop. If they don’t I’m going to ask my doctor for something else.” 

“I weighed in at 230 pounds when I began the treatment. Now I weigh 198 pounds and feel much fitter and happier.”

“Metermine helped me to lose 7 kilos, but I had to stop taking it because it made me fell very ill and ruined my concentration.”

Metermine Side Effects

Usage has been linked to numerous side effects. Some of the more commonly reported ones include:

  • Addiction
  • Skin irritations
  • Dry mouth
  • Dizziness
  • Headaches
  • Nausea
  • Mood changes
  • Chest pain
  • Blurred vision
  • Buzzing or ringing in the ears
  • Stomach cramps
  • Hypertension
  • Insomnia
  • Loss of consciousness
  • Tremors
  • Anxiety
  • Irritability
  • Mental confusion
  • Nervousness

Where to Buy Metermine

It should be possible to buy Metermine via your local pharmacy, but you will need a doctor’s prescription before you can do so and, unless you are significantly overweight, you are unlikely to obtain one. The law only allows doctors to prescribe to people who have a BMI of 30 or more. In some cases the threshold may be dropped to BMI 25, but only when people have other health problems, such as diabetes or sleep apnea.

The Final Verdict

Although Metermine has the ability to suppress the appetite and help people to lose weight, any results achieved can come at the price of unpleasant side effects.

It also has to be borne in mind the drug is only intended for short-term use and will not be able to go the distance and support dieters along the entire length of their weight loss journey.

Anyone who meets the criteria for a prescription will only continue to do so until their BMI reaches the threshold level. So anyone who gets a prescription because they have a BMI of 32 will be unable to continue the treatment when their BMI drops to 29.

PhenQ Australia fat burnerThe Metermine substitute, PhenQ, is a far better option. It provides dieters with long-term support and its blend of natural ingredients delivers a combination of appetite suppression, fat burning, and other benefits that make it a safer more powerful diet pill than Metermine.

We’re not putting down Phentermine-type drugs. They obviously have their place. We are merely pointing out safer options are available and hoping to discourage dieters from purchasing illegally via online sources.

View how PhenQ compares to other leading diet pills

Suprenza Phentermine – Uses, Side Effects and Stockists

Suprenza australiaSuprenza is a weight loss medication that contains the drug Phentermine. People living in the US may be able to obtain it via their doctor, but Suprenza is not approved for use in Australia.

However, two other brands of Phentermine (Duromine and Metermine) are available via most pharmacies and can be purchased with a doctor’s prescription.

Phentermine usage can entail nasty side effects though, so doctor’s are only permitted to prescribe it to people whose level of obesity is so high it likely to cause or aggravate other health issues.

Differences Between Suprenza, Duromine, and Metermine

Other than the name on the box, there is no difference between Duromine and Metermine. Both drugs are produced in capsule format and are available in 15mg, 30mg, and 40mg strength options.

Suprenza is a dispersible tablet that dissolves on the tongue and does not present problems to people who find it hard to swallow normal-type pills. The three strength options available are 15mg, 30mg, and 37.5mg.

Duromine is arguably the most well known of the Phentermine brands – it is prescription only.

Read more on Duromine

How Do Suprenza Tablets Help People Lose Weight

appetite for foodIt is an anorectic drug that helps keep the appetite under control. The level of appetite suppression experienced can vary from one person to the next, but most users find the drug makes it easier for them to eat less food.

This lowers the daily calorie intake and generally causes the body to become so short of calories it begins burning its reserves of fat to get extra energy.

However, it is important to be aware Suprenza is intended to be used alongside a calorie controlled diet and exercise. People who do not use the drug in this way may find the drug fails to deliver maximum weight loss.

Main Ingredients

A single (one tablet) dose provides 15 mg, 30 mg, or 37.5 mg of Phentermine hydrochloride. There are no other active weight loss ingredients, but several other compounds are necessary to enable smooth dispersal of the tablets on the tongue and to provide colour and flavour.

  • Citric acid powder
  • Mannitol powder
  • Povidone CL
  • Sucralose
  • Povidone K 30
  • Magnesium stearate
  • Talc
  • Sodium lauryl sulfate
  • Mannitol pregranulated
  • Peppermint flavour
  • FD&C Blue # 1 lake and FD&C Yellow # 5 lake (15mg tablet)
  • FD&C Yellow # 5 lake (30mg tablet)
  • FD&C Blue # 1 lake (37.5mg tablet)

How to Use – it is a short-term weight loss solution that can be used for a maximum of 12 weeks. The normal dose is one tablet each morning. It should be placed on the tongue and swallowed after it has dissolved. The medication is intended to be used with diet and exercise and is unlikely to provide good results if used alone.

Suprenza Customer Comments

A few sample customer testimonials read:

“I’ve always liked my food so I was a pretty big guy by the time I reached 20 and was already having problems with my knee joints and got out of breath a lot. Cutting back on food was hard. I felt hungry all the time. These pills help a lot and I am now losing around 7 pounds a week on average.”

“I’ve been taking Suprenza every day for six weeks and it has helped me to lose 28lbs. It’s a really good appetite suppressant, but you need to eat right and exercise too.” 

“Easy to take and good for controlling hunger. I’ve lost nearly 20lbs so far, but I’ve been having a lot of problems with itchy skin. It’s really annoying and not pleasant at all.”

“Managed to get hold of some tablets via a friend from America. They tasted terrible, made me feel sick and gave me a pounding headache. I don’t think they suppressed my appetite, but I felt so crook I couldn’t eat anything anyway. Threw them away.” 

Product Suitability and Side Effects

It is unsuitable for people who have certain health maladies. It can also react badly with some medications, so a doctor is the best person to decide if it is safe weight loss option for each potential user’s situation and needs.

The drug can also cause numerous side effects including, addiction, high blood pressure and mental confusion; so its usage requires the correct medical supervision. Alcohol is another big no-no for Suprenza users.

Combining the two can have serious medical consequences. The dispersible nature of the tablets presents further possible problems because their use can irritate the mucosa of the mouth cavity. This makes the drug unsuitable for anyone with disorders of the mouth cavity or tongue.

Where to Buy Suprenza

Cannot be legally purchased in Australia. The Phentermine weight loss drugs Duromine and Metermine are available via all pharmacies and have the same hunger suppressing ability, but they cannot be purchased without a doctor’s prescription.

Some online stores based in other parts of the world sell Suprenza, but it is illegal to buy Suprenza online and import it into the country. It is also important to note using without the necessary medical supervision is dangerous and can present great risks to the health.

The Final Verdict

Many dieters consider Phentermine to be the Holy Grail of weight loss, but its reputation is exaggerated.

There can be no doubt about its appetite controlling ability, but many modern supplements can provide this benefit without presenting the same risk of side effects.

Buy PhenQ in AustraliaThe most popular Phentermine substitute is a diet pill called PhenQ and the combination of appetite suppression, fat blocking, fat burning, and other benefits it provides allow it to deliver fantastic results.

Many dieters who have used both products say PhenQ leaves Phentermine eating its dust.

Unlike the drug it is designed to replace, PhenQ comes with a money back guarantee and it’s powered by plant extracts and other natural ingredients that can provide side effect-free weight loss, so it’s a much better option than Suprenza and other Phentermine diet pills.

Click here to read more on PhenQ